When someone drinks alcohol or uses certain drugs on a repeated basis, their brain adjusts to the presence of this substance. They become physiologically dependent on their substance of choice and utterly reliant on it to function and feel “normal.” In people who develop significant levels of dependence, withdrawal from drugs is often an inevitable response to the sudden absence of a drug’s declining concentration. Withdrawal symptoms may develop when a substance-dependent person quits a substance “cold turkey” or substantially reduces how much they are using. During withdrawal, the body is attempting to reach a new state of homeostasis as it dispels the user’s drug of choice. This can result in large fluctuations in brain chemicals and may accompany significant mental and physical health repercussions. Drug withdrawal may include a combination of physical, mental, and emotional symptoms — some of which can prove dangerous if left unmanaged.